Dare to double spare?

Dare to discipline.

Boosting NAD to spare hearing.

Ex vivo experiments have strangely shown that inhibition or stimulation of NAD metabolism can be neuroprotective. In this issue of Cell Metabolism, Brown et al. (2014) demonstrate that cochlear NAD is diminished by deafening noise but protected by nicotinamide riboside or WldS mutation. Hearing protection by nicotinamide riboside depends on Sirt3.

DARE: Desire to Strive Beyond Current Capabilities

The purpose of the following study is to explore the psychological practice and racing experience of competitive distance runners. It is proposed that a new mindset called DARE state be used to describe the mental experience of athletes when they are engaged in training that encompasses a “love of challenge,” deliberate practice and flow state in the same workout or race. The presence of both d...

UvA - DARE

The near horizon limit of the extremal BTZ black hole is a “self-dual orbifold” of AdS3. This geometry has a null circle on its boundary, and thus the dual field theory is a Discrete Light Cone Quantized (DLCQ) two dimensional CFT. The same geometry can be compactified to two dimensions giving AdS2 with a constant electric field. The kinematics of the DLCQ show that in a consistent quantum theo...

Inner Workings: Spacecraft dare to fly close to the sun.

A wide swath of North America was reminded during last summer’s eclipse that you can’t stare at the sun without protection. But to study the sun, space probes have to do much more than stare. They have to get extremely close to the sun’s unforgiving environs. Next year, two solar missions will do exactly that— traveling tens of millions of miles to study the sun’s outer atmosphere, its corona, ...